| John
Irwin is a research scientist in the Department of Pharmaceutical
Chemistry at the University of California, San Francisco
in the group of Brian Shoichet. Dr. Irwin received his
PhD in Organic Chemistry at the ETH in Zurich in 1991.
After working briefly at a startup company developing
molecular modeling software, he joined the lab of Gerard
Bricogne at the MRC Laboratory of Molecular Biology
in Cambridge, England developing new methods of macromolecular
structure determination. He developed one of the early
web-based graphical interfaces in structural biology.
He went on to join the Macromolecular Structural Database
project at the EMBL-EBI also in Cambridge where he was
part of a team transforming the Protein Databank into
an Oracle database and developing research tools. He
joined the Shoichet Lab while still at Northwestern
in 2000 and moved to UCSF in 2003. His work focuses
on improving virtual screening methods, and on lowering
the barriers to entry to docking for non-specialists.
Dr. Irwin has consulted on drug discovery projects for
a number of pharmaceutical companies. |
